{"product_id":"edvotek-activity-kit-cancer-gene-detection","title":"Edvotek Activity Kit - Cancer Gene Detection","description":"\u003cspan data-contrast=\"auto\"\u003eImmortality through uncontrolled cell division is a characteristic of cancer cells. The p53 gene is a tumour suppressor gene which prevents this. Mutations in this gene are present in more than 50% of cancers. Testing people for mutations in their p53 gene can indicate an increased risk in developing cancer. These tests raise intriguing ethical questions for both the individual tested and the family of an individual who chooses to be tested. In this experiment, students determine a pedigree for a family suspected to be carriers of mutations in their p53 genes. A DNA test indicates their likelihood of developing cancer.\u003c\/span\u003e\u003cspan data-ccp-props=\"{\"\u003e \u003c\/span\u003e\n\u003cul\u003e\n  \u003cli\u003e\n\u003cspan data-contrast=\"auto\"\u003eDiscover the molecular biology behind familial cancers\u003c\/span\u003e\u003cspan data-ccp-props=\"{\"\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n  \u003cli\u003e\n\u003cspan data-contrast=\"auto\"\u003eExplore how oncologists use pedigrees and molecular diagnostics\u003c\/span\u003e\u003cspan data-ccp-props=\"{\"\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n  \u003cli\u003e\n\u003cspan data-contrast=\"auto\"\u003eConstruct a family’s pedigree for Li-Fraumeni syndrome\u003c\/span\u003e\u003cspan data-ccp-props=\"{\"\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n  \u003cli\u003e\n\u003cspan data-contrast=\"auto\"\u003ePerform agarose gel electrophoresis to separate different sized DNA molecules\u003c\/span\u003e\u003cspan data-ccp-props=\"{\"\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n  \u003cli\u003e\n\u003cspan data-contrast=\"auto\"\u003eLoad, run, analyse, and size control samples and a patient’s blood, tumour, and tissue samples to identify mutations in their p53 gene\u003c\/span\u003e\u003cspan data-ccp-props=\"{\"\u003e \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"EDULAB","offers":[{"title":"Default Title","offer_id":42700468387901,"sku":"107K01523","price":899.85,"currency_code":"AED","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0637\/2583\/0205\/files\/edulab-science-life-science-default-title-edvotek-activity-kit-cancer-gene-detection-26761692545085.jpg?v=1770587304","url":"https:\/\/eduplaninternational.com\/products\/edvotek-activity-kit-cancer-gene-detection","provider":"Eduplan International","version":"1.0","type":"link"}